OB/Pediatrics

OBSTETRIC ANESTHESIA

PROJECT TITLE: Role of Pre-eclampsia in Cardiovascular Disease
PROJECT FACULTY: Sajid Shahul, MD
PROJECT DESCRIPTION:
The project investigates mechanisms of cardiac dysfunction in preeclampsia. Women with a history of preeclampsia (PE) are at increased risk of death from cardiovascular disease. I use a translational approach combining advanced echocardiography with biochemical signatures to detect subclinical cardiac changes in women with preeclampsia. This work is complemented by the use of large databases like the National Inpatient Sample (NIS) to uncover the epidemiology of preeclampsia.

PROJECT TITLE: Pulmonary Arterial Hypertension and Pregnancy
PROJECT FACULTY: Jennifer Banayan, MD
PROJECT DESCRIPTION:
The primary purpose of the study is to report the current incidence of pulmonary arterial hypertension during pregnancy at our institution. We aim to evaluate both maternal and fetal outcomes and trends: maternal mortality, neonatal prematurity, intra-uterine growth restriction, and peripartum mortality. 

PROJECT TITLE: General Anesthetics for Cesarean Section
PROJECT FACULTY: Jennifer Banyan, MD
PROJECT DESCRIPTION:
The rate of use of general anesthetics for cesarean delivery in the United States and factors associated with its use remain unknown. We propose to determine the rate and to identify factors associated with variability in the rates from three large administrative databases. One of them is the National Anesthesia Clinical Outcomes Registry, a sample representing over 22 million anesthetics from a variety of practice settings across the United States.

PROJECT TITLE: Pain and Analgesic Choices for Previable Vaginal Delivery
PROJECT FACULTY: Barbara Scavone, MD
PROJECT DESCRIPTION:
Little data exist regarding pain and analgesia for previable vaginal delivery. Ours is a unique prospective study gathering data on pain scores and analgesic choices for this procedure.

PROJECT TITLE: Obstetric Management of Super-Obese Patients
PROJECT FACULTY: Barbara Scavone, MD
PROJECT DESCRIPTION:
We compare outcomes among super-obese (BMI >/= 50), obese, and non-obese cohorts. Ours will be the largest sample describing anesthetic management of super-obese patients in the literature. We are prospectively assessing traditional palpation versus ultrasound guidance for obstetric neuraxial anesthetic techniques.

PROJECT TITLE: Microparticle Release and Obstetric Hemorrhage
PROJECT FACULTY: Barbara Scavone, MD
PROJECT DESCRIPTION:
This is a pilot study measuring the pattern of microparticle release over time during normal deliveries. We are using these data to plan for a study comparing microparticle patterns in patients who hemorrhage versus those who do not.

PEDIATRIC ANESTHESIA

PROJECT TITLE: Comparison of the LMA Flexible and Endotracheal Intubation for Adenotonsillectomy in Pediatric Patients. 
PROJECT FACULTY: Wendy Binstock, MD
PROJECT DESCRIPTION:
The use of the LMA Flexible has the potential to enhance positive outcomes and decrease the incidence of extubation-related complications in pediatric patients undergoing adenotonsillectomy, the most common surgical procedure in children. Alternative airway management and anesthesia techniques that may prove to be as safe and effective as current practice and could save time and decrease the cost of this procedure.

PROJECT TITLE: Pediatric Craniofacial Surgery Perioperative Registry.
PROJECT FACULTY: Wendy Binstock, MD
PROJECT DESCRIPTION:
In this study we collect multicenter data about the medical care of children undergoing craniofacial surgical procedures. The information is stored in a common database, and the data are available to all centers for research and quality improvement.

PROJECT TITLE: PeDI Registry
PROJECT FACULTY: Alina Lazar, MD
PROJECT DESCRIPTION:
The objective of the study is to input data into the PeDI Registry, a multi-center repository that documents intubation methods, techniques, personnel, and intubation-related adverse events after difficult direct laryngoscopy in children during anesthesia management. With benchmarking data from participating sites, difficult airway management practices can be compared. The registry will continually analyze and plot trends in practice, such as evolution in the types of techniques and equipment employed.